ABSTRACT
Stenotrophomonas maltophila is an important Nosocomial Bacterial Pathogen. It is ubiquitous, non-fermentative gram negative bacillus previously known as Pseudomonas maltophila or Xanthomonas maltophila. It is usually of low virulence but now a day there is increased frequency of its isolation from hospitalized patients, especially patient with immunocompromised status. S maltophila infections include Bacteremia, Pneumonia, Urinary tract infection, Endocarditis, Meningitis, Peritonitis, Ocular infections, Septic arthritis & Cystic fibrosis. Treatment of S. maltophila infection is often difficult as it is resistant to commonly used antimicrobial agents and this antimicrobial resistance may emerge during therapy. Herewith we are reporting a case of bacteremia in a patient with viral encephalitis caused by Dengue Virus. Patient was treated successfully with Co-trimoxazole plus ticarcillin+clavulanic acid along with other supportive measures.